EpiStack

H-29 - The Xinyuan market, not the farms, was where civets were infected and the virus amplified and spilled to humans

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Properties9
type
hypothesis
id
H-29
state
dropped
question
In the wildlife-trade chain, where did SARS-CoV infection of civets and spillover to humans occur - at farms of origin or at live-animal markets?
statement
Palm civets were not infected on their farms of origin but became infected and amplified the SARS-CoV-like virus at the live-animal market, which then acted as the source of sporadic human SARS cases.
drop_reason
SARS-CoV market-vs-farm amplification precedent (civets infected at the live-animal market, not on farms); base-rate/analogy input about a different virus, carried by observations O-54..O-57. Not a MECE answer to any cluster's sub-question.
source
S-44 - Kan et al. 2005 — SARS-CoV-like virus in market civets vs farmed civets
locator
Discussion (market amplification)
quote
the Xinyuan animal market was likely the source of infection, where the virus was amplified, circulated, excreted though the respiratory and intestinal tracts of palm civets, and subsequently disseminated to cause sporadic disease in humans

Palm civets were not infected on their farms of origin but became infected and amplified the SARS-CoV-like virus at the live-animal market, which then acted as the source of sporadic human SARS cases.

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