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O-41 - In the balanced n=70 wildlife-stall set human mtDNA was uncorrelated with viral RNA while Malayan porcupine and Himalayan marmot mtDNA were significantly positively correlated

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type
observation
id
O-41
statement
In the balanced set of 70 wildlife-stall samples (all sequenced regardless of qPCR status), human mtDNA was not significantly correlated with SARS-CoV-2 RNA (Spearman rho=0.13, 95% CI [-0.09,0.34]; average mammal rho=0.08), whereas Malayan porcupine (rho=0.45, P<0.001) and Himalayan marmot (rho=0.34, P<0.033) mtDNA were significantly positively correlated after FDR (5%) correction.
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source
S-35 - Crits-Christoph et al. — Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic (Cell)
locator
Results (correlational analysis of the n=70 balanced set), Figure S4, Table S16
quote
there was no significant correlation between human mtDNA and SARS-CoV-2 RNA (ρ=0.13; 95% confidence interval [CI] [-0.09,0.34])
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The authors restrict the correlation to the 70 January-12 wildlife-stall samples (a balanced subset, all sequenced irrespective of positivity) rather than the full sequenced set. Human mtDNA does not track the virus; porcupine and marmot do (reflecting their concentration in stall A). Notably raccoon dog itself is not among the significantly positively-correlated species here. Same D-1 data that S-39 (Bloom) analyses with the opposite emphasis.

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