EpiStack

O-58 - SARS-CoV-2 RBD has six ACE2-contact residues, five differing from SARS-CoV

1 min read

Properties8
type
observation
id
O-58
statement
The SARS-CoV-2 receptor-binding domain carries six residues key to human-ACE2 binding (L455, F486, Q493, S494, N501, Y505); five of the six differ from the corresponding residues in SARS-CoV.
link_state
linked
source
S-46 - Andersen et al. 2020 — The Proximal Origin of SARS-CoV-2
locator
Section 'Notable features of the SARS-CoV-2 genome'
quote
Five of these six residues differ between SARS-CoV-2 and SARS-CoV
data_basis

The SARS-CoV-2 receptor-binding domain carries six residues key to human-ACE2 binding (L455, F486, Q493, S494, N501, Y505); five of the six differ from the corresponding residues in SARS-CoV.

Graph View

Show model graphinteractive Bayesian view — separate from the graph above
added after the FLF submission deadline

Backlinks