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O-76 - The PRRA furin-site insertion is out of frame relative to aligned RaTG13-MP789

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type
observation
id
O-76
statement
Aligned against RaTG13 and pangolin MP789, the PRRA insertion is out of reading frame: it splits the original serine codon TCA into a new serine codon (TCT) plus part of an alanine codon (GCA).
link_state
linked
source
S-54 - Segreto Deigin 2021 — The genetic structure of SARS-CoV-2 does not rule out a laboratory origin
locator
Section 'The furin cleavage site...'; Fig 3
quote
The insertion of the furin cleavage site in SARS-CoV-2 is not in frame with the rest of the sequence, when compared with the MP789 and the RaTG13 sequences
data_basis

Aligned against RaTG13 and pangolin MP789, the PRRA insertion is out of reading frame: it splits the original serine codon TCA into a new serine codon (TCT) plus part of an alanine codon (GCA).

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