EpiStack

O-11 - Natural SARS-CoV-2 outbreak in farmed mink with respiratory disease, elevated mortality and interstitial pneumonia on two Dutch farms

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Properties8
type
observation
id
O-11
statement
In April 2020 two Dutch mink farms (NB1, 13,700 animals; NB2, 7,500 animals) had a natural SARS-CoV-2 outbreak: respiratory disease (nasal discharge to severe distress) and elevated mortality (NB1 2.4% vs 0.6% expected; NB2 1.2% vs 0.6%, 19-30 April), with severe diffuse interstitial pneumonia on necropsy in 16/18 (NB1) and 12/18 (NB2) animals.
link_state
orphan
source
S-27 - Oreshkova et al. 2020 — SARS-CoV-2 outbreak on Dutch mink farms
locator
Results (Clinical signs, Pathology)
quote
16 of 18 animals from NB1 and 12 of 18 from NB2 had diffusely dark to mottled red, wet lung lobes that did not collapse
data_basis

Respiratory disease was reported 19-20 April 2020. Signs were “mostly limited to watery nasal discharge, but some animals showed severe respiratory distress”. Mortality over 19-30 April rose to 2.4% (NB1) and 1.2% (NB2) against an expected 0.6%. Histology showed “severe diffuse interstitial pneumonia with hyperaemia, alveolar damage and loss of air containing alveolar lumina”. This is a natural (not experimentally dosed) infection of a farmed mustelid.

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