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O-63 - RaTG13 is ~96% genome-identical to SARS-CoV-2 but its RBD diverges

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Properties7
type
observation
id
O-63
statement
The bat coronavirus RaTG13 (from Rhinolophus affinis) is ~96% identical to SARS-CoV-2 across the whole genome - the closest known relative - but its RBD diverges and is predicted not to bind human ACE2 efficiently.
link_state
orphan
source
S-46 - Andersen et al. 2020 — The Proximal Origin of SARS-CoV-2
locator
Section 'Notable features' / 'Origins'
data_basis

The bat coronavirus RaTG13 (from Rhinolophus affinis) is ~96% identical to SARS-CoV-2 across the whole genome - the closest known relative - but its RBD diverges and is predicted not to bind human ACE2 efficiently.

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