summary - Prospective cohort of 21,327 male US physicians (Physicians’ Health Study I), egg intake by abbreviated food questionnaire, ~20-year average follow-up (1550 MIs, 1342 strokes, 5169 deaths). Egg consumption was not associated with incident MI or stroke overall, but all-cause mortality rose with intake (HR 1.23 for at least 7/wk vs <1/wk, P-trend<0.0001) - an association roughly twice as strong among the diabetic subgroup (HR 2.01 highest vs lowest category, P-interaction=0.09).
relevance_note - A harm-finding source specifically for mortality (not events) in an all-male professional cohort; its diabetic-subgroup finding previews the heterogeneity slice 3 covers in depth, but the general-population result belongs here.