O-62 - SARS-CoV-2 backbone matches no previously described coronavirus reverse-genetics system
The SARS-CoV-2 genomic backbone is not derived from, and does not match, any previously described/used coronavirus backbone or published reverse-genetics platform.
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Why this is evidence
A backbone matching no previously described reverse-genetics system undercuts assembly from a recognised published platform — favouring H-41/H-42 over the in-vitro-assembly flavour of H-43 (which must posit a novel/undisclosed backbone).