EpiStack

H-24 - SARS-CoV-2 emerged at the Huanan market rather than circulating in the Wuhan community beforehand

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Properties8
type
hypothesis
id
H-24
state
merged
question
Did SARS-CoV-2 first emerge at the Huanan market or circulate in the community before it?
statement
SARS-CoV-2 first emerged and began spreading at/around the Huanan market itself (the market was the origin/epicenter of the outbreak), rather than the market outbreak being a downstream amplification of pre-existing, unrelated community transmission in Wuhan.
merged_into
H-14 - The market environmental pattern reflects wildlife-associated emergence at the Huanan market
source
S-35 - Crits-Christoph et al. — Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic (Cell)
locator
Results (genetic diversity consistent with market emergence); Discussion

Argued from the market-associated genomes’ tMRCA matching the pandemic tMRCA and both lineages A and B being present at the market. Competes with the pre-market community-circulation / market-as-amplifier reading (e.g. Bloom 2021).

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added after the FLF submission deadline

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