EpiStack

H-36 - Wild bat sarbecoviruses able to infect humans via hACE2 without adaptation circulate in the Indochinese peninsula

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Properties9
type
hypothesis
id
H-36
state
merged
question
Do naturally occurring wild bat viruses capable of infecting humans via hACE2 exist without lab adaptation?
statement
SARS-CoV-2-like bat sarbecoviruses that bind human ACE2 and enter/replicate in human cells with no laboratory adaptation circulate naturally in Rhinolophus bats of the Indochinese peninsula (northern Laos).
merged_into
H-41 - Natural zoonotic spillover with no research involvement
source
S-52 - Temmam et al. 2022 Nature — BANAL Laos bat coronaviruses
locator
Abstract / Discussion
quote
bat-borne SARS-CoV-2-like viruses that are potentially infectious for humans circulate in Rhinolophus spp. in the Indochinese peninsula

SARS-CoV-2-like bat sarbecoviruses that bind human ACE2 and enter/replicate in human cells with no laboratory adaptation circulate naturally in Rhinolophus bats of the Indochinese peninsula (northern Laos).

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