O-18 - Harvard egg-T2D association stronger at lower overall diet quality (AHEI interaction)

O-18 — Effect-modification analysis stratifying the pooled association by Alternative Healthy Eating Index.

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Why this is evidence

A significant egg-T2D interaction with overall diet quality shows the effect is contingent on background diet, cutting against a fixed intrinsic property (H-17) and supporting background-diet-indexing (H-38). Direction (more harmful at lower diet quality) is opposite to H-38’s specific refined-carb-displacement mechanism, so it evidences background-diet contingency generally more than H-38’s particular direction.