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H-20 - In dysglycemic adults, replacing high-carb breakfast foods with eggs modestly worsens LDL-C

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Properties8
type
hypothesis
id
H-20
state
active
question
Does egg consumption worsen LDL-C relative to high-carbohydrate substitutes?
statement
In adults with metabolic syndrome/prediabetes, substituting ~2 eggs/day for energy-matched higher-carbohydrate breakfast foods produces a modestly less favorable LDL-C trajectory (a small adverse lipid effect relative to the high-carb comparator).
cluster
HC-6 - Effect of egg-egg-cholesterol intake on the atherogenic blood-lipid profile
source
S-57 - Substituting eggs for high-carbohydrate breakfast foods, at-risk-for-T2D (Maki 2020)
locator
Results/Discussion, LDL-C between-diet difference

Uncertain because n=30, the difference clusters near p~0.02 among several endpoints without multiple-testing correction, and LDL-C fell in absolute terms on both conditions (the effect is a smaller decrease, not a rise).

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