EpiStack

H-14 - Egg-T2D association is positive in US populations but null in non-US (European and Japanese) populations

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Properties8
type
hypothesis
id
H-14
state
merged
question
Does the association between egg consumption and type 2 diabetes risk differ between US and non-US populations?
statement
The association between egg consumption and incident T2D is population-specific: positive in US cohorts (HR ~1.18 per 3 eggs/week) but null in non-US (European and Japanese) cohorts.
merged_into
H-8 - Egg-T2D association is region-population-dependent - positive in US, null in Europe, null-to-inverse in Asia
source
S-8 - Wallin 2016 Diabetologia - egg consumption and T2D in the Cohort of Swedish Men + updated dose-response meta-analysis
locator
Discussion

H-14 — The heterogeneity is the paper’s headline: a single pooled estimate is misleading because the US and non-US strata point different ways.

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