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O-107 - No change in hsCRP or oxidized LDL after egg doses despite the TMAO rise

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Properties7
type
observation
id
O-107
statement
Despite the dose-dependent TMAO rise, there was no difference in high-sensitivity C-reactive protein (hsCRP) or oxidized LDL between plasma collected before and 24 h after each egg dose (paired tests, P>0.05).
link_state
linked
source
S-47 - Effect of egg ingestion on trimethylamine-N-oxide production in humans- a randomized, controlled, dose-response study (Miller et al. 2014, AJCN)
locator
Results (hsCRP, oxidized LDL)
quote
There was no difference in hsCRP or oxidized LDL concentrations after egg doses.

The two measured downstream harm surrogates (inflammation, LDL oxidation) did not move acutely with the TMAO rise; short 24-h window and n=6 limit power.

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