Category HRs vs never/rarely: 1-3/month 0.86 (0.79-0.93); 1-3/week 0.82 (0.76-0.88); 4-6/week 0.77 (0.70-0.86); daily 0.74 (0.67-0.82). This is a substantially larger effect than for coronary or ischaemic-stroke endpoints.