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O-31 - Wallin meta-analysis US-vs-non-US split - egg-T2D HR 1.18 (US, I2 0%) vs 0.97 (non-US)

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Properties8
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observation
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O-31
statement
In the 12-cohort meta-analysis the per-3-eggs/week HR for T2D was 1.18 (95% CI 1.13-1.24) across 5 US studies with no between-study heterogeneity (I2 0%), versus 0.97 (95% CI 0.90-1.05) across 7 non-US (European + Japanese) studies (I2 78%) - a positive, internally-consistent US signal against a null non-US estimate.
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S-8 - Wallin 2016 Diabetologia - egg consumption and T2D in the Cohort of Swedish Men + updated dose-response meta-analysis
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Results; meta-analysis, US vs non-US stratification
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quote
1.18...in five US studies...and 0.97...in seven non-US studies

O-31 — A second, independent restatement (before Drouin-Chartier 2020) of the US/non-US heterogeneity, but built on the same overlapping cohort set.

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