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O-77 - No significant dose response of HDL cholesterol or triglycerides to dietary cholesterol

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Properties7
type
observation
id
O-77
statement
Across the four egg/cholesterol doses there was no significant dose response for HDL cholesterol or for triglycerides; the dietary-cholesterol effect fell essentially entirely on LDL/total cholesterol, not HDL.
link_state
linked
source
S-42 - Ginsberg 1994 Arterioscler Thromb — dose-response of dietary cholesterol-egg feeding on lipoproteins in healthy young men
locator
Abstract; Results
quote
no significant dose responses for either triglycerides or HDL cholesterol

Corrects the step-2 node title (‘LDL and HDL both rise’): HDL did NOT show a significant dose response in this trial. Because HDL was flat while LDL rose, the total/HDL and LDL/HDL ratios worsened with added dietary cholesterol.

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