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O-86 - In PURE one or more eggs per day not associated with composite CVD-mortality, total mortality, or major CVD

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Properties7
type
observation
id
O-86
statement
Among 146,011 PURE adults (median 9.5 y follow-up; 14,700 composite events) without prior CVD, >=7 vs <1 egg/week showed no significant association with the composite of death or major CVD (HR 0.96, 95% CI 0.89-1.04, P-trend 0.74), total mortality (1.04, 0.94-1.15, P-trend 0.38), major CVD (0.92, 0.83-1.01, P-trend 0.20), cardiovascular mortality (1.00, 0.85-1.19), stroke (0.97, 0.84-1.13) or heart failure (1.24, 0.90-1.70; ns).
link_state
linked
source
S-91 - PURE study- egg intake, blood lipids, CVD and mortality in 50 countries (Dehghan 2020)
locator
Results; Table 3
quote
we did not find significant associations between egg intake and blood lipids, mortality, or major CVD events

Cox frailty model with center random intercepts (adjusts region/country); covariates age, sex, education, urban/rural, smoking, physical activity, diabetes history, intakes of fruit/vegetables/red meat/poultry/fish/dairy, % energy from carbohydrate, total energy. Dose-response (per +0.5 egg/day) and cubic-spline analyses also null (P-trend >0.10). Further adjustment for blood cholesterol did not change results.

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