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O-89 - In 31544 vascular-disease patients ONTARGET TRANSCEND egg intake not associated with CVD or mortality

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Properties6
type
observation
id
O-89
statement
In 31,544 patients with vascular disease or diabetes with end-organ damage (ONTARGET/TRANSCEND, median 4.7 y follow-up), >=7 vs <1 egg/week showed no significant association with the composite outcome (HR 0.97, 0.76-1.25), total mortality (0.88, 0.62-1.24), major CVD (0.97, 0.73-1.29) or MI (1.12, 0.68-1.82); a positive trend for heart failure was noted (P-trend 0.01, top-category HR 1.25, 0.74-2.11).
link_state
linked
source
S-91 - PURE study- egg intake, blood lipids, CVD and mortality in 50 countries (Dehghan 2020)
locator
Results; Table 4

These are secondary-prevention patients (aged >=55 y with prior coronary/peripheral/cerebrovascular disease or complicated diabetes) on cardiovascular medications; qualitative FFQ, models adjusted for BMI, medication, trial allocation and dietary covariates. The null replicates PURE’s neutral finding in a higher-risk population.

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