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O-53 - The primary outcome, IVGTT-derived whole-body insulin sensitivity index, did not differ between egg and high-carb breakfasts

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type
observation
id
O-53
statement
The trial's pre-specified primary outcome — the IVGTT-derived insulin sensitivity index (ISI) — did not differ significantly between conditions (egg +15.0% vs non-egg -4.1%, P=0.193), directionally favoring eggs but non-significant; HOMA2-%S (P=0.067) and fasting insulin (P=0.057) were likewise non-significant.
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S-57 - Substituting eggs for high-carbohydrate breakfast foods, at-risk-for-T2D (Maki 2020)
locator
Results, primary outcome (insulin sensitivity index)
quote
ISI: Egg 15.0% (14.3), Non-Egg -4.1% (16.8), p = 0.193

Important nuance: the favorable glycemic signal in this trial sits on a secondary measure (HOMA-IR), while the pre-specified primary insulin-sensitivity endpoint was null. Baseline ISI 8.9 x 10^-4.

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