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EpiStack v1 — FLF competition

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analysis tests

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covid1

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hypotheses

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dropped

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H 4 SARS CoV 2 originated by natural evolution in a wild bat reservoir capable of infecting human cells

H-4 - SARS-CoV-2 originated by natural evolution in a wild bat reservoir capable of infecting human cells

Properties10
type
hypothesis
id
H-4
state
dropped
question
What is the evolutionary origin of SARS-CoV-2?
statement
SARS-CoV-2 arose by natural recombination/evolution in wild Rhinolophus bats, a reservoir already harbouring human-ACE2-binding, human-cell-infectious SARS-CoV-2-like viruses (BANAL clade).
source
S-12 - Temmam 2022 Nature - BANAL bat coronaviruses from Laos are SARS-CoV-2's closest known relatives and infect human cells
locator
Discussion
drop_reason
Follows its 4a merge survivor H-3, which 4b dropped: the natural-bat-reservoir claim is compatible with every member of HC-1 (natural evolution then market spillover, or natural evolution then collection and lab escape), so it is background rather than a competing answer to the route question; its discriminating natural-vs-engineered content is scored once inside H-5.
former_merged_into
H-3 - SARS-CoV-2 originated by natural evolution in a bat sarbecovirus reservoir
merge_note
Absorbed into H-3 at 4a (state was `merged`); re-dispositioned to `dropped` when 4b dropped H-3, since a `merged` node must resolve in one hop to an `active` survivor. Original 4a merge recorded in `former_merged_into` and in H-3's `merged_from`.

Graph View

Backlinks

  • H-3 - SARS-CoV-2 originated by natural evolution in a bat sarbecovirus reservoir
  • S-12 - Temmam 2022 Nature - BANAL bat coronaviruses from Laos are SARS-CoV-2's closest known relatives and infect human cells

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