O-20 - Egg intake was not significantly associated with blood lipids, mortality, or major CVD in the PURE 21-country cohort
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Why this is evidence
Per-member (H-2, H-3, H-4, H-9, H-10, H-12):
- H-2: disconfirmed (no protection on major CVD).
- H-3: disconfirmed (no mortality harm).
- H-4: predicted, though PURE’s endpoint set is wider than H-4’s IHD scope.
- H-9: predicted but only partially in scope - PURE is mostly non-Western.
- H-10: this is its defining confirmation - diverse global populations across income levels, null on lipids, CVD and mortality alike.
- H-12: mildly disconfirmed - a strongly direction-varying effect would be expected to surface as heterogeneity somewhere across 21 countries.