Folder: v1/analysis-tests/eggs1/evidence-links

Jul 20, 2026

E-1 - O-1 × HC-1 — one egg-day raised LDL-C 12% and ApoB 9%

Jul 20, 2026

E-10 - O-8 × HC-3 — egg-mortality association twice as strong in diabetics

Jul 20, 2026

E-11 - O-16 × HC-3 — individual cholesterol responsiveness reproducible across repeated trials

Jul 20, 2026

E-12 - O-17 × HC-3 — responsiveness independent of habitual intake and body weight

Jul 20, 2026

E-13 - O-18 × HC-3 — smooth square-root dose-response across 227 metabolic-ward men

Jul 20, 2026

E-14 - O-4 x HC-2 - CKB dose-response inverse association with CVD-IHD-stroke

Jul 20, 2026

E-15 - O-5 x HC-2 - CKB 18 percent lower CVD mortality with daily eggs

Jul 20, 2026

E-16 - O-6 x HC-2 - No egg-MI-stroke association in the Physicians Health Study

Jul 20, 2026

E-17 - O-7 x HC-2 - All-cause mortality rose with egg intake in PHS (HR 1.23)

Jul 20, 2026

E-18 - O-8 x HC-2 - Egg-mortality association twice as strong in diabetic PHS subgroup

Jul 20, 2026

E-19 - O-9 x HC-2 - EPIC modest inverse egg-IHD association

Jul 20, 2026

E-2 - O-2 × HC-1 — lipid effect confined to LDL-ApoB, HDL and TG unchanged

Jul 20, 2026

E-20 - O-10 x HC-2 - EPIC inverse association vanishes after 4-year lag exclusion

Jul 20, 2026

E-21 - O-19 x HC-2 - No egg-CVD association up to 1-day in pooled Harvard cohorts

Jul 20, 2026

E-22 - O-20 x HC-2 - PURE 21-country null for lipids, mortality and major CVD

Jul 20, 2026

E-23 - O-21 x HC-2 - PURE-only lower-MI signal failed to replicate in ONTARGET-TRANSCEND

Jul 20, 2026

E-3 - O-11 × HC-1 — whole-egg cholesterol poorly absorbed

Jul 20, 2026

E-4 - O-12 × HC-1 — acute whole-egg meal did not raise plasma total cholesterol

Jul 20, 2026

E-5 - O-13 × HC-1 — 2 eggs-day for 3 months produced no between-group lipid difference

Jul 20, 2026

E-6 - O-17 × HC-1 — responsiveness uncorrelated with habitual cholesterol intake

Jul 20, 2026

E-7 - O-18 × HC-1 — serum cholesterol rises with dietary cholesterol with square-root diminishing returns

Jul 20, 2026

E-8 - O-20 × HC-1 — no association between egg intake and blood lipids in PURE

Jul 20, 2026

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Folder: v1/analysis-tests/eggs1/evidence-links

E-1 - O-1 × HC-1 — one egg-day raised LDL-C 12% and ApoB 9%

E-10 - O-8 × HC-3 — egg-mortality association twice as strong in diabetics

E-11 - O-16 × HC-3 — individual cholesterol responsiveness reproducible across repeated trials

E-12 - O-17 × HC-3 — responsiveness independent of habitual intake and body weight

E-13 - O-18 × HC-3 — smooth square-root dose-response across 227 metabolic-ward men

E-14 - O-4 x HC-2 - CKB dose-response inverse association with CVD-IHD-stroke

E-15 - O-5 x HC-2 - CKB 18 percent lower CVD mortality with daily eggs

E-16 - O-6 x HC-2 - No egg-MI-stroke association in the Physicians Health Study

E-17 - O-7 x HC-2 - All-cause mortality rose with egg intake in PHS (HR 1.23)

E-18 - O-8 x HC-2 - Egg-mortality association twice as strong in diabetic PHS subgroup

E-19 - O-9 x HC-2 - EPIC modest inverse egg-IHD association

E-2 - O-2 × HC-1 — lipid effect confined to LDL-ApoB, HDL and TG unchanged

E-20 - O-10 x HC-2 - EPIC inverse association vanishes after 4-year lag exclusion

E-21 - O-19 x HC-2 - No egg-CVD association up to 1-day in pooled Harvard cohorts

E-22 - O-20 x HC-2 - PURE 21-country null for lipids, mortality and major CVD

E-23 - O-21 x HC-2 - PURE-only lower-MI signal failed to replicate in ONTARGET-TRANSCEND

E-3 - O-11 × HC-1 — whole-egg cholesterol poorly absorbed

E-4 - O-12 × HC-1 — acute whole-egg meal did not raise plasma total cholesterol

E-5 - O-13 × HC-1 — 2 eggs-day for 3 months produced no between-group lipid difference

E-6 - O-17 × HC-1 — responsiveness uncorrelated with habitual cholesterol intake

E-7 - O-18 × HC-1 — serum cholesterol rises with dietary cholesterol with square-root diminishing returns

E-8 - O-20 × HC-1 — no association between egg intake and blood lipids in PURE

E-9 - O-13 × HC-3 — no lipid difference from 2 eggs-day in prediabetes-T2D

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