summary - 28 overweight/obese men (40-70y) on a carbohydrate-restricted weight-loss diet were given 3 eggs/day for 12 weeks. Dietary cholesterol from the eggs raised plasma HDL-C significantly without a corresponding adverse change in LDL-C, so the LDL-C/HDL-C ratio was maintained in both hyper- and hypo-responders to dietary cholesterol.
relevance_note - Shows the lipid response to egg cholesterol is diet-context dependent (low-carbohydrate background), with HDL rising alongside any LDL change - a null/pro-egg anchor from the Fernandez-lab line named in the brief.