summary - 40 hyperlipidemic adults; an acute phase (single high-egg meal) plus a 6-week sustained phase compared 2 eggs/day + egg substitute against egg substitute alone. Over 6 weeks whole-egg intake left LDL-C essentially unchanged (-2 mg/dL, ns) and endothelial function (FMD) unchanged, while the cholesterol-free substitute produced significantly larger LDL-C/total-cholesterol reductions and FMD improvement.
relevance_note - Tests eggs against a real cholesterol-free substitute product (not just an egg-free diet) in a higher-baseline-risk (hyperlipidemic) population, still finding no significant LDL rise from whole eggs.