O-69 - BANAL RBDs match 15-16 of 17 hACE2-contact residues vs only 11-17 for RaTG13
Of the 17 RBD residues that contact human ACE2, 16/17 are conserved in BANAL-52/103 (one mismatch, H498Q) and 15/17 in BANAL-236 (K493Q, H498Q), versus only 13/17 for the Cambodian R. shameli virus and 11/17 for RaTG13 - the BANAL RBDs are far closer to SARS-CoV-2 at the receptor interface than RaTG13.
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Why this is evidence
Wild BANAL RBDs matching 15-16 of 17 hACE2-contact residues (vs 11/17 for RaTG13) show human-binding RBDs exist in nature without adaptation — favouring H-41/H-42 over lab-adapted H-43.