O-77 - No significant dose response of HDL cholesterol or triglycerides to dietary cholesterol
Corrects the step-2 node title (‘LDL and HDL both rise’): HDL did NOT show a significant dose response in this trial. Because HDL was flat while LDL rose, the total/HDL and LDL/HDL ratios worsened with added dietary cholesterol.
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Why this is evidence
The rise loading onto LDL with HDL flat matches H-34 (rise borne by LDL/apoB, not HDL) and contradicts H-40’s HDL-up response.