O-106 - Marked inter-individual variation in egg-to-TMAO conversion (-=4-fold), all subjects converted, men more than women
The 4-fold spread on n=6 flags a large host/microbiome effect on TMAO generation, though no discrete non-converter phenotype appeared.
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Why this is evidence
Every subject converted egg choline to TMAO (no non-converter phenotype), which supports H-42’s “egg choline measurably enters the pathway” against H-28’s form-limited/negligible reading. The ~4-fold host/sex spread is the kind of person-specific effect H-56 (some other relationship) would emphasise.