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H-21 - Moderate egg intake has no causal effect on CVD risk overall

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Properties11
type
hypothesis
id
H-21
state
active
question
What is the overall effect of moderate egg consumption on CVD risk?
statement
Moderate egg consumption (up to ~1 egg/day) has no causal effect on cardiovascular disease or all-cause mortality risk in the general adult population, a neutrality that holds across low-, middle- and high-income populations.
cluster
HC-1 - Overall net effect of moderate habitual egg intake on cardiovascular disease and mortality
source
S-19 - Drouin-Chartier 2020 BMJ - egg consumption and CVD in NHS, NHSII, HPFS
merged_from
additional_sources
locator
  • S-19: Discussion, Principal findings
  • S-91: Discussion / Conclusion
generalization_note
Widened from CVD-only in the general (US-cohort) population to CVD and all-cause mortality holding across income levels globally; gave up the population-uniformity claim, which is carried by the separate region/background-diet heterogeneity hypotheses (H-22, H-38).

The paper’s principal interpretation: the adjusted null and near-null narrow CIs indicate no clinically meaningful effect of moderate egg intake on CVD.

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