summary - Randomized double-blind crossover in 17 lacto-vegetarian college students: one extra-large egg/day for 3 weeks (raising dietary cholesterol from 97 to 418 mg/day) versus an isocaloric egg-free period. LDL-C was 12% higher and ApoB 9% higher during the egg period; HDL-C, ApoA-I, ApoA-II, VLDL-C and total triglycerides did not change significantly.
relevance_note - Ecologically realistic single-food (not purified-cholesterol) feeding study showing a clean LDL/ApoB-specific rise with HDL untouched - a “rise” anchor, in tension with the search plan’s framing of it as a null-finding source.