Classic standalone Framingham Study analysis: nutrient intake was assessed in a subsample in 1957, yielding egg-consumption estimates for 912 subjects. Serum-cholesterol distribution curves were almost identical across tertiles of egg intake, and no relationship was found between egg intake and coronary heart disease incidence; the authors concluded that, within this population’s range of intake, differences in egg consumption were unrelated to blood cholesterol level or CHD incidence. relevance_note: An early, frequently-cited null result that directly contradicted the dietary guidance of its era (limit eggs for cholesterol) — a genuinely distinct, small, historical Western cohort family from the Harvard/US-pooled/PHS lines.