Dose-escalation randomised feeding trial in a healthy population, comparing 0, 1, 2, and 3 eggs/day (each dose ~4 weeks) layered onto a carbohydrate-restricted weight-loss diet. HDL-C rose and the LDL:HDL ratio fell with increasing egg dose while LDL-C itself did not change; plasma choline rose dose-dependently with intake while plasma TMAO stayed flat. Lipids are the paper’s headline framing (title leads with HDL); the TMAO finding is a secondary reassurance measure relevant to slice 7 as well. relevance_note: A dose-response whole-egg RCT showing the lipid profile improves (HDL up, LDL flat) with increasing egg intake in healthy adults — key pro-egg/null mechanism anchor; also relevant to the independent TMAO pathway (slice 7 may mine it via found_via).
Consolidator (step 1c) merge note: TRUE duplicate of S-48 - Intake of up to 3 eggs-day increases HDL cholesterol and plasma choline while plasma TMAO is unchanged in a healthy population (DiMarco et al. 2017, Lipids).md — same paper (DiMarco et al. 2017, Lipids, DOI 10.1007/s11745-017-4230-9), minted independently by slice 7 (S-48, TMAO headline) and slice 4 (this node, HDL headline) — exactly the 4/7-boundary double-mint the planner flagged. Survivor is the lower id S-48; this node is retained but flagged duplicate_of.